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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3B3
All Species:
50.61
Human Site:
T153
Identified Species:
74.22
UniProt:
Q15393
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15393
NP_036558.3
1217
135577
T153
R
D
A
A
A
R
L
T
I
S
S
P
L
E
A
Chimpanzee
Pan troglodytes
XP_511081
1283
142840
T219
R
D
A
A
A
R
L
T
I
S
S
P
L
E
A
Rhesus Macaque
Macaca mulatta
XP_001107025
1199
133593
T147
L
E
A
H
K
A
N
T
L
V
Y
H
V
V
G
Dog
Lupus familis
XP_536791
1217
135545
T153
R
D
A
A
A
R
L
T
I
S
S
P
L
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q921M3
1217
135532
T153
R
D
A
A
A
R
L
T
I
S
S
P
L
E
A
Rat
Rattus norvegicus
XP_001077410
1216
135436
T153
R
D
A
A
A
R
L
T
I
S
S
P
L
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506454
1217
135474
T153
R
D
A
A
A
R
L
T
I
S
S
P
L
E
A
Chicken
Gallus gallus
XP_001232348
1218
135585
T153
R
D
A
A
A
R
L
T
I
S
S
P
L
E
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LVE8
1217
135603
T153
R
D
A
A
A
R
L
T
I
S
S
P
L
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728546
1227
136598
T153
R
D
T
Q
A
R
L
T
I
S
S
P
L
E
A
Honey Bee
Apis mellifera
XP_623333
1217
135272
T153
R
D
P
E
A
R
L
T
I
S
S
P
L
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188711
1141
126889
R146
L
G
L
N
H
V
V
R
K
Y
S
E
P
L
E
Poplar Tree
Populus trichocarpa
XP_002312063
1213
134429
T152
R
D
T
V
A
R
L
T
I
S
S
P
L
E
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49552
1088
121161
T115
S
D
R
I
G
R
P
T
D
N
G
Q
I
G
I
Baker's Yeast
Sacchar. cerevisiae
Q04693
1361
153766
I202
I
D
P
N
G
R
C
I
I
L
S
S
V
E
Q
Red Bread Mold
Neurospora crassa
Q7RYR4
1209
134021
T159
R
N
S
Q
A
E
L
T
I
S
S
P
L
E
A
Conservation
Percent
Protein Identity:
100
94.8
98.1
99.9
N.A.
99.9
99.5
N.A.
99.6
99
N.A.
93.4
N.A.
75.4
80.5
N.A.
76.1
Protein Similarity:
100
94.8
98.2
100
N.A.
100
99.5
N.A.
99.9
99.6
N.A.
97.9
N.A.
86.9
90.2
N.A.
85.7
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
6.6
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
13.3
Percent
Protein Identity:
58.7
N.A.
N.A.
23.5
23
51
Protein Similarity:
76.1
N.A.
N.A.
42
41.5
69.5
P-Site Identity:
86.6
N.A.
N.A.
20
33.3
73.3
P-Site Similarity:
86.6
N.A.
N.A.
33.3
40
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
57
50
75
7
0
0
0
0
0
0
0
0
75
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
82
0
0
0
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
7
0
7
0
7
0
0
0
0
0
7
0
82
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
13
0
0
0
0
0
7
0
0
7
7
% G
% His:
0
0
0
7
7
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
7
0
0
7
0
0
0
7
82
0
0
0
7
0
7
% I
% Lys:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% K
% Leu:
13
0
7
0
0
0
75
0
7
7
0
0
75
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
13
0
0
7
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
13
0
0
0
7
0
0
0
0
75
7
0
0
% P
% Gln:
0
0
0
13
0
0
0
0
0
0
0
7
0
0
7
% Q
% Arg:
75
0
7
0
0
82
0
7
0
0
0
0
0
0
0
% R
% Ser:
7
0
7
0
0
0
0
0
0
75
88
7
0
0
0
% S
% Thr:
0
0
13
0
0
0
0
88
0
0
0
0
0
0
0
% T
% Val:
0
0
0
7
0
7
7
0
0
7
0
0
13
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _